Minocycline

Description

What is Minocycline?

Minocycline is a tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. It has a role as an antibacterial drug and an Escherichia coli metabolite. It is a member of tetracyclines, a tetracenomycin and a tertiary alpha-hydroxy ketone. It is a conjugate acid of a minocycline(1-). It is a tautomer of a minocycline zwitterion. (Source: ChEBI)

Basic information

Product Name:	Minocycline
Synonyms:	minocyclin; Minociclina; Minocyn; Minocyclinum; Tri-minocycline; Borymycin;
CAS:	10118-90-8
MF:	C23H27N3O7
MW:	457.48
EINECS:	800-277-5

Chemical Structure

Minocycline

Chemical Properties

alpha	D25 -166° (c = 0.524)
Boiling point	563.31°C (rough estimate)
density	1.3283 (rough estimate)
refractive index	1.6500 (estimate)
pka	pKa 2.8 (Uncertain);5.0 (Uncertain);7.8 (Uncertain);9.5 (Uncertain)
Water Solubility	52g/L(25 ºC)

Minocycline Uses And Synthesis

Minocycline belongs to the class of medications called tetracycline antibiotics, who has a broader spectrum than the other members of the group. Identified as a long-acting type, it is used to treat infections induced by certain kinds of bacteria. Minocycline is commonly used in the treatment of skin infections, such as inflammatory lesions of non-nodular moderate-to-severe acne vulgaris. It is also used for other skin infections, such as MRSA and Lyme disease. Besides, minocycline is effective to treat urinary tract infections, gallbladder infections, and respiratory tract infections like bronchitis, pneumonia, sinusitis and it is also used for treating Rocky Mountain spotted fever, typhus and other infections caused by the typhus group of bacteria and tick fevers caused by rickettsiae, etc.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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