Author:Site Editor Publish Time: 2021-11-17 Origin:Site
In medical research, the significance of compound prescriptions lies in the use of two or more drugs in combination to maximize the synergistic effects of drugs. From this perspective, it seems that compounding is better than unilateral. However, the combined use of the compound must have a clear purpose and scientific basis.
Quercetin is a bioflavonoid. Citrus flavonoids and rutin are also known as bioflavonoids. However, one of the two is a glycoside and the other is an aglycon. Take rutin as an example: One molecule of rutin is removed from a molecule of rhamnose and glucose to become quercetin, that is, quercetin is the aglycon of rutin. Similarly, quercetin is also the aglycone of hesperidin. Simply put: rutin and hesperidin are more primary forms of quercetin. Quercetin can only be obtained after repurification. Why do you want to do this? The price of quercetin is more expensive than the price of rutin and hesperidin. In addition to marketing gimmicks, more importantly, the cost is low. In addition to this, why not buy pure quercetin when considering to buy such a compound product?
Conclusion: The compound combination of quercetin + rutin + hesperidin is the combination of quercetin primary form. The purity of quercetin is low, and the purpose is to reduce costs.
Bromelain, also known as bromelain powder, has anti-inflammatory and anti-edema effects. Bromelain is mainly used clinically for the adjuvant treatment of infection and inflammation after surgery. Regarding the combination of quercetin and bromelain, a prospective randomized, double-blind, placebo-controlled trial of the National Institutes of Health (NIH) for Type III chronic prostatitis syndrome confirmed that taking quercetin, pineapple Protease and papain supplements can enhance the absorption of bioflavonoids. Compared with patients taking placebo, 67% of patients improved their symptoms by at least 25%.
Conclusion: The combination of quercetin + bromelain is scientifically based. The presence of bromelain enhances the absorption of quercetin and makes quercetin more effective. However, as an enzyme preparation, bromelain is strictly regulated by the US FDA and Health Canada: the product packaging must indicate the amount of enzyme activity. If the bromelain product without indicating the enzyme activity is either bromelain only added as an excipient, then the content is very small and the effect is negligible; or it is an informal product. Therefore, you need to pay special attention to the nutritional composition table when purchasing.
Curcumin is a natural compound with good anti-inflammatory and anti-cancer properties. At the same time, curcumin has the effects of lowering blood lipids, anti-tumor, anti-inflammatory, choleretic, and antioxidant. Regarding the combination of quercetin and curcumin, a clinical study for gastric cancer showed that curcumin has the effects of anti-angiogenesis, anti-proliferation, anti-metastasis, pro-apoptosis and anti-Helicobacter. Quercetin has been shown to inhibit cell growth and induce apoptosis, necrosis and autophagy as well as anti-Helicobacter activity. In clinical studies, curcumin and quercetin have a combined synergistic effect, which seems to be a good candidate drug for the treatment of gastric cancer by promoting apoptosis, anti-proliferation and anti-Helicobacter pylori activity.
Another study on lung cancer showed:
Morphological and histological analysis of lung tumor nodules confirmed that the preventive treatment of curcumin and quercetin induced lung tumor cell apoptosis by regulating p53.
Conclusion: The combination of turmeric and quercetin is scientifically based. The combined synergistic effect of turmeric and quercetin can inhibit the development of tumor cells through the effects of promoting apoptosis and anti-proliferation. Such turmeric and quercetin compound products are more targeted, and are suitable for middle-aged and elderly patients and patients in the recovery stage of cancer. Of course, turmeric quercetin can also be used for daily health care.
Maxmedchem could offer One-Stop Service Solution customizable for our valued customers regarding to quercetin compound or quercetin powder . We focus on all stages of the manufacturing process from raw materials to final ingredients and its application solutions industries.
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