Tetrahydrocurcumin vs curcumin

Tetrahydrocurcumin and curcumin source difference

Curcumin is extracted from the rhizome of the ginger plant Curcuma longa. The market specification is 95%. Tetrahydrocurcumin is obtained by further hydrogenation of curcumin, which is equivalent to molecular re-modification, and the common market specification is 98%.

Tetrahydrocurcumin and curcumin difference in molecular structure

Tetrahydrocurcumin has fewer unsaturated C=C double bonds than curcumin in structure, so it lacks the conjugated double bonds required by the chromophore. Therefore, in terms of appearance and color, tetrahydrocurcumin changes from curcumin’s yellow color. Into a white powder.

Because of the unsaturated C=C double bond, if curcumin is stored for a long time or in the heating process of health care products, the C=C double bond may be forcibly oxidized or broken by high temperature, which directly affects the efficacy of curcumin.

Tetrahydrocurcumin and curcumin difference in stability

Tetrahydrocurcumin is obviously superior to curcumin in high temperature stability.

Because of this, the bioavailability of tetrahydrocurcumin is much higher than that of curcumin. There are many limitations in clinical application Because curcumin is not easily absorbed and transformed through the gastrointestinal tract.

Therefore, Tetrahydrocurcumin is considered to have better pharmacological effects than curcumin due to its chemical stability and higher antioxidant properties.

Tetrahydrocurcumin and curcumin basically have the same effect

Compared with curcumin, tetrahydrocurcumin is more stable and has higher antioxidant properties, so its bioavailability is high and it is more widely used, but the basic effects of the two are the same.

(1) Anti-inflammatory effect

(2) Antioxidant effect

(3) Whitening and freckle removal effect

Tetrahydrocurcumin IC50 is 0.000492 ppm (curcumin 0.730 ppm, kojic acid 9.14 ppm). Tetrahydrocurcumin has a much better whitening effect, and its white color makes it more convenient to use in cosmetics.

(4) Promoting wound healing

It is mainly manifested in the promotion of the production of β-transforming growth factor (TGF-β) and collagen, and the regeneration of epidermal cells.

Usages of tetrahydrocurcumin and curcumin

Because of its yellow color and low cost, curcumin is mostly used as an active ingredient in health products and functional foods, or as a natural coloring agent in foods.

Tetrahydrocurcumin, because of its white color and high cost, is mostly used in high-end cosmetics. Its whitening effect is even better than the whitening star arbutin in the cosmetics industry.

Committed to natural cosmetics raw materials, and through continuous upgrading of the process, it produces tetrahydrocurcumin that is in line with cosmetics whitening and freckle removal, with white color, high content and low cost.

How about Tetrahydrocurcumin price of Maxmedchem?

We could supply both natural Tetrahydrocurcumin and Synthetic Tetrahydrocurcumin from our factory. From the market view, our Tetrahydrocurcumin price is really competitive according to the feedback of our customers.