Thiamine HCL

Description

What is Thiamine Hydrochloride?

Thiamine Hydrochloride is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, thiamine hydrochloride is phosphorylated by thiamine diphosphokinase to form active thiamine pyrophosphate (TPP), also known as cocarboxylase. TPP is a coenzyme for many enzymatic activities involving fatty acid, amino acid and carbohydrate metabolism.(

Basic information

Product Name:	Thiamine hydrochloride
Synonyms:	VIT B1; VITAMIN B1 HCL; VITAMIN B1 HYDROCHLORIDE; THIAMINE; THIAMINE CHLORIDE HYDROCHLORIDE; THIAMINE HCL; THIAMINE HYDROCHLORIDE
CAS:	67-03-8
MF:	C12H17N4OS.ClH.Cl
MW:	337.27
EINECS:	200-641-8
Product Categories:	Inhibitors; Biochemistry; Vitamin B1;Vitamin Ingredients; Intermediates & Fine Chemicals; Pharmaceuticals; Vitamins

Chemical Structure

Thiamine hydrochloride

Chemical Properties

Melting point	250 °C (dec.)(lit.)
density	1.3766 (rough estimate)
FEMA	3322 \| THIAMINE HYDROCHLORIDE
refractive index	1.6000 (estimate)
Fp	9°C
storage temp.	room temp
solubility	H₂O: 0.1 g/mL at 20 °C, clear, colorless
form	Crystalline Powder
pka	pKa 4.8 (Uncertain);9.0 (Uncertain)
color	White to almost white
PH	2.7-3.3
Water Solubility	1 g/mL
Sensitive	Light Sensitive & Hygroscopic
Merck	14,9295
JECFA Number	1030
BRN	3851771
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents, strong reducing agents.

Thiamine hydrochloride Uses

Thiamine hydrochloride is a hydrochloride obtained by combining thiamine chloride with one molar equivalent of hydrochloric acid. It has a role as an insect repellent. It is a vitamin B1 and a hydrochloride. It contains a thiamine(2+).

Thiamine is a essential nutrient required for carbohydrate metabolism, also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products , vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to Thiamine diphosphate, a coenzyme in the decarboxylation of α-keto acids. Chronic deficiency may lead t o neurological impairment, bariberi, Wernicke-Korsakoff syndrome.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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