Tramadol hydrochloride’s precautions for use

Why we need to use tramadol hydrochloride?

Cancer is a malignant tumor originating from epithelial tissue, which is the most common type of malignant tumor. Generally, what people call “cancer” is used to refer to all malignant tumors. Cancer often causes severe pain that requires prompt medication for relief. Tramadol hydrochloride can be used for various acute and chronic pains such as cancer pain, fracture or postoperative pain.

What’s more, cancer is a general term for a large group of malignant tumors. Cancer cells are characterized by unrestricted and endless proliferation, which consumes a lot of nutrients in the patient’s body; cancer cells release a variety of toxins, causing a series of symptoms in the human body; cancer cells can also metastasize to all parts of the body to grow and reproduce, It can lead to weight loss, weakness, anemia, loss of appetite, fever, and severe organ dysfunction. Cancer (malignant tumor) can also destroy the structure and function of tissues and organs, causing necrosis and hemorrhage combined with infection, and patients eventually die due to organ failure.

The expansive growth or rupture of the tumor, infection, etc., may stimulate or oppress the peripheral nerves or nerve trunks, and local pain may occur. Pain often indicates that the cancer has entered the middle or advanced stage. The beginning is mostly dull or dull pain, which is obvious at night. After that, it gradually worsened and became unbearable, day and night, especially at night.

Tramadol hydrochloride is a powerful non-morphine analgesic. Mainly acts on specific receptors related to pain in the central nervous system. There is no smooth muscle spasm and obvious respiratory depression, and the analgesic effect can be maintained for 4-6 hours. It can prolong the duration of barbiturate anesthesia and enhance the analgesic effect when used with tranquilizers. It also has mild drug resistance and dependence.

What should I pay attention to when using tramadol hydrochloride?

1. People with functional insufficiency and patients with heart disease should reduce the dose or use it with caution.

2. Not to be used together with monoamine oxidase inhibitors.

3. The dose should be reduced when used in combination with central tranquilizers (such as diazepam, etc.).

4. Long-term use cannot rule out the possibility of drug resistance or drug dependence. However, it cannot be used as a substitute for opioid-dependent patients because it cannot suppress the withdrawal symptoms of morphine.

5. Patients with drug abuse or dependence tendencies can only use it for a short period of time.

In addition, the adverse reactions of taking tramadol hydrochloride tablets are sweating, drowsiness, dizziness, nausea, vomiting, anorexia and dysuria. Individual cases have allergic reactions such as skin rash and lowering of blood pressure.

For tramadol hydrochloride tablets, they are contraindicated in patients with acute poisoning of alcohol, sleeping pills, analgesics or other central nervous system-acting drugs. The combination of tramadol hydrochloride tablets with ethanol, sedatives, analgesics or other psychotropic drugs can cause acute poisoning. Appropriate dose reduction, combined with barbiturates can prolong the anesthesia time and so on.

Where could I buy tramadol hydrochloride?

Tramadol hydrochloride (CAS No.: 36282-47-0) has been one of main APIs product used for medicine production according to its benefits.While, Maxmedchem, as one of suppliers, has been working at this ingredients for over ten years. The tramadol hydrochloride powder supplied from maxmedchem has been used for tablets, capsules production so far.

The advantages of Maxmedchem:

-GMP standard factory

-Excellent R&D team

-Competitive price

-Quality is under controlled

-MSDS or COA could be offered

Welcome to contact us at: info@maxmedchem.com for more details.