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6-Aminopenicillanic Acid (551-16-6) C8H12N2O3S

  • Chemical Name:6-Aminopenicillanic acid
  • CAS No.:551-16-6
  • MF: C8H12N2O3S
  • MW:216.26
  • Specification: USP|EP|BP
  • Purity: 95%-99% or As customer requested
  • Appearance: White to cream Powder
  • Solubility:Soluble in water and hydrochoric acid.
  • Product Categories: Chemical Intermediate; Biochemistry; API; Organic acids
  • Test method: HPLC
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6-aminopenicillanic acid is a penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics. It has a role as an allergen. It derives from a penicillanic acid. It is a conjugate base of a 6-aminopenicillanate. It is a tautomer of a 6-aminopenicillanic acid zwitterion.

6 aminopenicillanic acid Basic information  
Product Name: 6-Aminopenicillanic acid
Synonyms: 6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;6-APA;(+)-6-AMINOPENICILLANIC ACID; 6-AMINOPENICILLANIC ACID; 6-AMINO PENICILLINIC ACID; 7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID; (25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
CAS: 551-16-6
MF: C8H12N2O3S
MW: 216.26
EINECS: 208-993-4
Product Categories: Chemical Intermediate; Antibiotics for Research and Experimental Use; beta-Lactams ;Biochemistry; API; Organic acids
Mol File: 551-16-6.mol

6 aminopenicillanic acid Chemical Structure

6-Aminopenicillanic acid            

6 apa Chemical Properties   

Melting point  198-200 °C (dec.)(lit.)
alpha  276.3 º (c=1.2, 0.1N HCl 22 ºC)
Boiling point  460.2±45.0 °C(Predicted)
density  1.3418 (rough estimate)
refractive index  1.6300 (estimate)
storage temp.  2-8°C
solubility  2.46g/l
pka pKa 2.3 (Uncertain)
form  Fine Powder
color  White to cream
PH 3.4 (100g/l, H2O)
optical activity [α]22/D +276.3°, c = 1.2 in 0.1 M HCl
Water Solubility  Soluble in water and hydrochoric acid.
Merck  14,458
BRN  15080
InChIKey NGHVIOIJCVXTGV-SDKNWNMFSA-N
CAS DataBase Reference 551-16-6(CAS DataBase Reference)
EPA Substance Registry System 6-Aminopenicillanic acid (551-16-6)

Penin Usage And Synthesis


Chemical Properties WHITE TO CREAM FINE POWDER
Uses (+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
Definition ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.
Safety Profile Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

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