Chlortetracycline Hydrochloride

Description

Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. It is also bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain.

This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.

Chlortetracycline hydrochloride Basic information

Product Name:	Chlortetracycline hydrochloride
Synonyms:	7-CHLORTETRACYCLINE MONOHYDROCHLORIDE; 7-CHLOROTETRACYCLINE HCL; 7-CHLOROTETRACYCLINE HYDROCHLORIDE; 7-CHLOROTETRACYCLINE MONOHYDROCHLORIDE;
CAS:	64-72-2
MF:	C22H24Cl2N2O8
MW:	515.34
EINECS:	200-591-7
Product Categories:	AUREOMYCIN; Intermediates & Fine Chemicals; Pharmaceuticals; Inhibitors

Chlortetracycline hydrochloride Chemical Structure

Chlortetracycline hydrochloride

Chlortetracycline hcl Chemical Properties

Melting point	210-215 °C (dec.)(lit.)
alpha	D23 -240°
storage temp.	2-8°C
solubility	1 M NaOH: soluble50mg/mL
form	Powder
color	faint yellow to yellow
pka	3.3(at 25℃)
Water Solubility	Soluble in water
Sensitive	Light Sensitive
Merck	13,2211
BRN	3858364

Chlortetracycline hcl Usage And Synthesis

Chemical Properties	Yellow Solid
Uses	antibacterial, antiamebic, Ca chelator, hepatotoxic; inhibits protein synthesis
	Chlortetracycline is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial.
	Chlortetracycline hydrochloride is a salt prepared from chlortetracycline taking advantage of the basic dimethylamino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, chlortetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
	An antimicrobial and antibacterial. This compound contains an undetermined amount of epi-chlortetracycline