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Parecoxib Sodium is a water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous or intramuscular administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib. Valdecoxib selectively binds to and inhibits COX-2. This prevents the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and, therefore, does not interfere with blood coagulation.
Product Name: | PARECOXIB SODIUM |
Synonyms: | sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide; sodium salt; parecoxib sodium salt; Dynastat; |
CAS: | 198470-85-8 |
MF: | C19H17N2NaO4S |
MW: | 392.40405 |
EINECS: | 813-689-5 |
Product Categories: | Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals |
Mol File: | 198470-85-8.mol |
Melting point: | 273-275°C |
storage temp. | Refrigerator |
Chemical Properties: | White Solid |
Uses | Anti-inflammatory, analgesic. |
Parecoxib Sodium is indicated for relief of the signs and symptoms of osteoarthritis.
For relief of the signs and symptoms of rheumatoid arthritis in adults.
For relief of the signs and symptoms of particular or poly articular course Juvenile Rheumatoid Arthritis (JRA) in patients.
For the management of acute pain in adults.
For the treatment of primary dysmenorrhea.
For the acute treatment of migrain attacks with or without aura in adults.
The safety and effectiveness of Parecoxib have not been established for cluster headache, which is present in an older, predominantly male, population.
Email us at: info@maxmedchem.com
Parecoxib Sodium is a water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous or intramuscular administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib. Valdecoxib selectively binds to and inhibits COX-2. This prevents the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and, therefore, does not interfere with blood coagulation.
Product Name: | PARECOXIB SODIUM |
Synonyms: | sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide; sodium salt; parecoxib sodium salt; Dynastat; |
CAS: | 198470-85-8 |
MF: | C19H17N2NaO4S |
MW: | 392.40405 |
EINECS: | 813-689-5 |
Product Categories: | Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals |
Mol File: | 198470-85-8.mol |
Melting point: | 273-275°C |
storage temp. | Refrigerator |
Chemical Properties: | White Solid |
Uses | Anti-inflammatory, analgesic. |
Parecoxib Sodium is indicated for relief of the signs and symptoms of osteoarthritis.
For relief of the signs and symptoms of rheumatoid arthritis in adults.
For relief of the signs and symptoms of particular or poly articular course Juvenile Rheumatoid Arthritis (JRA) in patients.
For the management of acute pain in adults.
For the treatment of primary dysmenorrhea.
For the acute treatment of migrain attacks with or without aura in adults.
The safety and effectiveness of Parecoxib have not been established for cluster headache, which is present in an older, predominantly male, population.
Email us at: info@maxmedchem.com
Are you interested in our PARECOXIB SODIUM Now?
Please contact with info@maxmedchem.com
Q1: | Can I get some samples of PARECOXIB SODIUM CAS 198470-85-8 ? |
A: | Yes, we can supply the free sample, you just pay for freight. |
Q2: | How to start orders or make payments? |
A: | Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Escrow. |
Q3: | What's your MOQ? |
A: | Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid. |
Q4: | How about delivery time? |
A: | About 3-5 days after payment confirmed. |
Q5: | Is there a discount? |
A: | Different quantity has different discount. |
Q6: | How do you treat quality complaint? |
A: | First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. |
Are you interested in our PARECOXIB SODIUM Now?
Please contact with info@maxmedchem.com
Q1: | Can I get some samples of PARECOXIB SODIUM CAS 198470-85-8 ? |
A: | Yes, we can supply the free sample, you just pay for freight. |
Q2: | How to start orders or make payments? |
A: | Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Escrow. |
Q3: | What's your MOQ? |
A: | Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid. |
Q4: | How about delivery time? |
A: | About 3-5 days after payment confirmed. |
Q5: | Is there a discount? |
A: | Different quantity has different discount. |
Q6: | How do you treat quality complaint? |
A: | First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. |