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What is L-Ergothioneine: Anti-oxidation Cosmetic Raw Material

What is L-Ergothioneine?

l-ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent antioxidant activities.




What is the best source of L-Ergothioneine?

l ergothioneine mushrooms are the highest dietary source for the unique sulfur-containing antioxidant ergothioneine.


L-Ergothioneine best time to take?

This can be taken any time of the day l-ergothioneine powder with or without food.


How much L-Ergothioneine per day?

Doses up to 25 mg have been safely used in clinical studies, but there is no clinical evidence to indicate whether these doses improve health outcomes. The European Commission concluded that ergothioneine supplements are likely safe up to 30 mg/day for adults and 20 mg/day for children.


Is L-Ergothioneine a longevity vitamin?

“An increasing body of evidence suggests ergothioneine powder may be an important dietary nutrient for the prevention of a variety of inflammatory and cardiometabolic diseases; and ergothioneine has alternately been suggested as a vitamin, ‘longevity vitamin’​ and nutraceutical,” they wrote.


L-Ergothioneine Health Benefits

  • l-ergothioneine offers powerful cellular protection against oxidative stress.
  • May support healthy cellular aging by delaying telomere shortening.
  • May support cognitive1, vision6 and heart health.


Why is L-Ergothioneine good for the brain?

In vitro observations suggest that ERGO benefits brain function through both its antioxidative activity and by promoting neurogenesis and neuronal maturation.


Is L-Ergothioneine an anti inflammatory?

l-ergothioneine (EGT), a hydrophilic compound with specific transporter known as OCTN1, has been shown to exert anti-ageing properties. In addition to its antioxidant effect, EGT has been reported to have anti-senescence, anti-inflammatory and anti-neurodegenerative properties.


What are the benefits associated with L-Ergothioneine capsules?

l-ergothioneine supplements benefits is exceptional in that it can reach the very core of certain cells such as erythrocytes, unlike other classic antioxidants such as vitamins C and E. It crosses the cell membrane thanks to a transporter, the OCTN1 protein. It is thus a potent intracellular antioxidant, as important as L-glutathione. In addition, it has also been shown to be a powerful chelator, enabling it to bind to toxic heavy metals, while protecting blood cells from all types of damage.

Encouraged by its antioxidant properties, researchers subsequently investigated its anti-inflammatory effects, since ergothioneine acts on, amongst others, the pro-inflammatory cytokine, interleukin. Ergothioneine therefore has multiple properties actively working inside the human body:

  • Neutralises reactive oxygen molecules (free radicals), thus combatting oxidative stress and reducing damage to mitochondrial DNA, oxidation of proteins and lipid peroxidation.
  • Chelates – or traps – various positive metallic cations.
  • Can activate antioxidant enzymes such as glutathione peroxidase or SOD, while inhibiting enzymes that generate the superoxide radical.
  • Reduces oxidation of various haemoproteins such as haemoglobin and myoglobin.
  • Protects mitochondria.
  • Reduces the harmful effects of UV rays.
  • Preserves and maintains levels of other antioxidants such as vitamins C and E, glutathione and SOD.
  • Protects the brain from neurotoxins and thus plays a preventive role against cognitive decline.
  • Encourages cellular respiration and fat lipolysis, thus increasing energy and stamina for physical exercise.
  • When combined with hyaluronic acid, glucosamine, collagen and cat’s claw, it was shown to significantly reduce joint pain and increase joint mobility, associated in particular with poor postural work habits, after just six weeks’ use.

Wholesale L-Ergothioneine Powder to benefit from its antioxidant and anti-inflammatory power.


What is the use of L-Ergothioneine in cosmetics?

l-ergothioneine can be adapted to most formulations due to its excellent efficacy, stability and water-solubility. Furthermore, EGT produced by biosynthesis technology has a higher purity and sustainability than natural extracts.


L-Ergothioneine cosmetic raw material

Maxmedchem cosmetic ingredient manufacturers l-ergothioneine is obtained by multi-fermentation of Hericium. Multi-fermentation can increase the yield of L-Ergothioneine, which is a sulfur-containing derivative of the amino acid histidine.




How is L-Ergothioneine made?

l-ergothioneine is synthesised by a variety of microbes, especially fungi (including in mushroom fruiting bodies) and actinobacteria, but is not synthesised by plants and animals who acquire it via the soil and their diet, respectively.


Ergothioneine: A Compound of the Future

We thus guarantee the best concentrations of active ingredients in our products. perhaps you are working on the R&D of your new product, and l-ergothioneine powder for your formula. As l-ergothioneine powder manufacturer, ✨ Want to try a sample? Request one here.






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